Anthony C Keech Selected Research

Fenofibrate (CiL)

1/2022	Fenofibrate, which reduces risk of sight-threatening diabetic retinopathy in type 2 diabetes, is associated with early narrowing of retinal venules: a FIELD trial substudy.
7/2021	The relationship of neutrophil elastase and proteinase 3 with risk factors, and chronic complications in type 2 diabetes: A Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) sub-study.
1/2021	Relationship of low molecular weight fluorophore levels with clinical factors and fenofibrate effects in adults with type 2 diabetes.
11/2020	Relationships of adipocyte-fatty acid binding protein and lipocalin 2 with risk factors and chronic complications in type 2 diabetes and effects of fenofibrate: A fenofibrate Intervention and event lowering in diabetes sub-study.
1/2020	Uric acid predicts long-term cardiovascular risk in type 2 diabetes but does not mediate the benefits of fenofibrate: The FIELD study.
1/2019	Fenofibrate Rescues Diabetes-Related Impairment of Ischemia-Mediated Angiogenesis by PPARα-Independent Modulation of Thioredoxin-Interacting Protein.
7/2018	Fenofibrate effects on carotid artery intima-media thickness in adults with type 2 diabetes mellitus: A FIELD substudy.
1/2018	Effect of fenofibrate on uric acid and gout in type 2 diabetes: a post-hoc analysis of the randomised, controlled FIELD study.
1/2018	Predicting the Effect of Fenofibrate on Cardiovascular Risk for Individual Patients With Type 2 Diabetes.
7/2017	Baseline Circulating FGF21 Concentrations and Increase after Fenofibrate Treatment Predict More Rapid Glycemic Progression in Type 2 Diabetes: Results from the FIELD Study.

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Anthony C Keech Research Topics

Disease

38	Type 2 Diabetes Mellitus (MODY) 01/2022 - 11/2006
28	Cardiovascular Diseases (Cardiovascular Disease) 12/2021 - 11/2006
19	Myocardial Infarction 03/2022 - 01/2010
13	Stroke (Strokes) 03/2022 - 12/2006
11	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2022 - 01/2013
11	Coronary Disease (Coronary Heart Disease) 12/2021 - 01/2009
10	Atherosclerosis 10/2021 - 11/2006
9	Inflammation (Inflammations) 07/2021 - 12/2008
6	Unstable Angina 03/2022 - 10/2013
6	Diabetic Retinopathy (Retinopathy, Diabetic) 01/2022 - 01/2013
5	Insulin Resistance 11/2020 - 08/2014
5	Hypertension (High Blood Pressure) 01/2020 - 11/2011
4	Diabetes Complications 01/2022 - 01/2009
4	Hypoglycemia (Reactive Hypoglycemia) 01/2022 - 05/2012
4	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2021 - 11/2006
4	Diabetes Mellitus 01/2021 - 01/2020
4	Acute Coronary Syndrome 01/2020 - 11/2005
4	Dyslipidemias (Dyslipidemia) 07/2018 - 11/2006
3	Heart Failure 06/2022 - 01/2009
3	Ischemic Stroke 12/2021 - 03/2013
3	Peripheral Arterial Disease 01/2021 - 01/2018
3	Venous Thromboembolism 01/2020 - 12/2012
3	Overweight 01/2019 - 01/2018
3	Weight Loss (Weight Reduction) 01/2019 - 01/2018
2	Coronary Artery Disease (Coronary Atherosclerosis) 01/2021 - 01/2018
2	Atrial Fibrillation 01/2021 - 09/2013
2	Genetic Risk Score 01/2020 - 01/2020
2	Venous Thrombosis (Deep-Vein Thrombosis) 01/2020 - 12/2012
2	Pulmonary Embolism 01/2020 - 12/2012
2	Albuminuria 01/2019 - 01/2010
2	Ischemia 01/2019 - 01/2018
2	Chronic Kidney Failure (Chronic Renal Failure) 01/2019 - 02/2012
2	Prediabetic State (Prediabetes) 11/2018 - 12/2017
2	Vascular Diseases (Vascular Disease) 01/2018 - 03/2015
2	Neoplasms (Cancer) 01/2018 - 05/2016
2	Pancreatitis 12/2017 - 08/2012
2	Body Weight (Weight, Body) 04/2015 - 01/2015
1	Intermittent Claudication 01/2021
1	Cognitive Dysfunction 12/2020
1	Hemorrhagic Stroke 01/2020
1	ST Elevation Myocardial Infarction 01/2020
1	Sudden Death 01/2020

Drug/Important Bio-Agent (IBA)

34	Fenofibrate (CiL)FDA LinkGeneric 01/2022 - 11/2006
20	evolocumabIBA 12/2021 - 01/2017
16	LipidsIBA 07/2018 - 11/2006
15	LDL CholesterolIBA 10/2021 - 03/2013
15	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 10/2021 - 11/2006
10	Biomarkers (Surrogate Marker)IBA 01/2022 - 12/2008
10	Insulin (Novolin)FDA Link 09/2021 - 01/2010
7	Proprotein Convertase 9IBA 12/2021 - 10/2017
7	CholesterolIBA 12/2020 - 11/2011
6	Glucose (Dextrose)FDA LinkGeneric 01/2022 - 08/2014
6	oxidized low density lipoproteinIBA 10/2021 - 07/2016
6	CreatinineIBA 11/2020 - 06/2009
6	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 01/2019 - 12/2012
6	Pharmaceutical PreparationsIBA 10/2017 - 11/2006
5	Triglycerides (Triacylglycerol)IBA 11/2020 - 11/2011
5	fibroblast growth factor 21IBA 01/2019 - 12/2012
5	Pravastatin (Pravachol)FDA LinkGeneric 01/2018 - 10/2013
4	DNA (Deoxyribonucleic Acid)IBA 01/2022 - 01/2020
3	Retinaldehyde (Retinal)IBA 01/2022 - 01/2013
3	Uric Acid (Urate)IBA 01/2021 - 01/2018
3	HomocysteineIBA 11/2020 - 06/2009
3	C-Reactive ProteinIBA 01/2020 - 05/2016
3	HDL CholesterolIBA 01/2020 - 06/2009
3	HDL LipoproteinsIBA 01/2020 - 03/2013
3	lorcaserinIBA 01/2019 - 01/2018
3	5-HT2C Serotonin ReceptorIBA 01/2019 - 01/2018
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2019 - 01/2013
2	omega-Chloroacetophenone (Mace)IBA 03/2022 - 01/2021
2	CarbohydratesIBA 09/2021 - 01/2018
2	saxagliptin FDA Link 01/2021 - 01/2021
2	TicagrelorIBA 01/2021 - 01/2021
2	MicroRNAs (MicroRNA)IBA 01/2021 - 01/2020
2	Colchicine FDA LinkGeneric 01/2021 - 01/2020
2	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 01/2021 - 01/2021
2	Fatty Acid-Binding ProteinsIBA 11/2020 - 12/2012
2	AlbuminsIBA 01/2019 - 11/2014
2	Troponin IIBA 01/2018 - 02/2014
2	Therapeutic UsesIBA 10/2014 - 01/2013
2	Apolipoprotein A-I (Apolipoprotein A1)IBA 08/2014 - 06/2009
2	Fibric Acids (Fibrates)IBA 08/2012 - 11/2006
1	Myeloblastin (Proteinase 3)IBA 07/2021
1	Leukocyte Elastase (Neutrophil Elastase)IBA 07/2021
1	Factor Xa (Coagulation Factor Xa)IBA 01/2021
1	LeptinIBA 01/2021
1	mirabegronIBA 01/2021
1	C-PeptideIBA 01/2021
1	darapladibIBA 01/2021
1	Blood Glucose (Blood Sugar)IBA 12/2020
1	Lipocalin-2IBA 11/2020
1	alirocumabIBA 01/2020
1	Ezetimibe (Zetia)FDA Link 01/2020

Therapy/Procedure

25	Therapeutics 06/2022 - 02/2012
6	Surgical Amputation (Amputations) 12/2021 - 01/2009
4	Injections 09/2021 - 01/2018
2	Glycemic Control 12/2021 - 05/2012
2	Lasers (Laser) 04/2015 - 12/2013
2	Renal Dialysis (Hemodialysis) 02/2012 - 01/2009
1	Cerebral Revascularization 12/2021